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Repeated injection in the same location creates tissue changes over time
In individuals with obesity, the skin may have been stretched out for years to accommodate larger fat volumes, which can result in a loss of elasticity and slower spring back after significant weight loss

Your insulin dose may need to change because of: weight gain or loss, increased stress, illness, or change in diet or level of physical activity

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Of course, everyone's limits are different , so it's essential to listen to your body and know when to stop
