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After 12 months of treatment, compared with those on semaglutide alone, women who were taking both MHT and semaglutide: showed an improved weight loss response achieved about 30% more total body weight loss The reasons for this association are unknown, though the authors propose that it may be due to MHT improving other quality of life measures

There are also situations in which patients have been incorrectly placed on thyroid medication due to unknown reasons

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However, such intervention is highly invasive, has considerable risk and is irreversible and expensive

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