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PPAR- ligands may influence the activity of the reninangiotensin system by transcriptional regulation at both the mediator and receptor levels, in addition to lowering blood glucose levels

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doi: 10.1161/CIRCULATIONAHA.112.091215 39 GuoZQiWYuYDuSWuJLiuJ

Efficacy analysis was based on the intention-to-treat method

June 1, 2025

Related Stories Study links GLP-1 treatment to fewer alcohol drinking days Blood ketone threshold may help predict weight loss success Eight-hour eating window sustains long-term weight loss Simultaneously, a growing body of evidence suggests that Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) are capable of crossing the blood-brain barrier (BBB) and interacting with the brain's reward and dopamine signaling regions, leading researchers to hypothesize that these originally weight-management-centric drugs could be used to address addictive behaviors, specifically regarding the suppression of ethanol-seeking triggers