glp 1 pens Semaglutide vs. Other GLP-1 Receptor Agonists How GLP-1 medications are transforming

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GLP-1R agonist 2 (compound 2) is an effective GLP-1R agonist that exerts its activating effect by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues of GLP-1R

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The aim of the present review is to examine the cellular processes underlying the actions of these new, highly significant classes of peptide receptor agonists

Interestingly, glucagon-like peptide-1 receptor agonists (GLP-1RAs), used in the treatment of T2DM and obesity, are known to show pro-cognitive and neuroprotective properties, and exert modulatory effects on immune, endocrine and metabolic processes in the central nervous system