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STEP 2: EXFOLIATE Switch from physical exfoliators to gentle chemical exfoliators, such as the Enzyme Rescue Multi-Purpose Mask

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Method We systematically searched PubMed and Embase from inception to 1 May 2025 for cohort studies comparing the effect of combination therapy with SGLT2 inhibitor or GLP-1 RA monotherapy on (cardiovascular) mortality and cardiovascular or kidney endpoints in individuals with type 2 diabetes

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