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The most striking result is the suicidal ideations or attempts of the Ozempic group, which showed an approximately 2.4-fold increase in risk

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[DOI] [PMC free article] [PubMed] [Google Scholar] 174.Frates B

More safety data is still being studied

As the field advances, humanized preclinical systems that allow drug evaluation against human targetssuch as GCGR/GIPR/GLP1R humanized mouse modelswill play a pivotal role in bridging the gap between mechanistic discovery and clinical translation

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