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An increase in BAX/Bcl-2 ratio has been shown to result in memory loss and learning capacity deregulation in the cortex and hippocampus region [44]

Research has identified specific gene variants associated with GLP-1 drug response, but pharmacogenomic testing for GLP-1 medications is not yet standard clinical practice

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Tirzepatide, by contrast, showed no significant increase in biliary risk in the available data