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Rybelsus, another oral form of semaglutide, remains approved for type 2 diabetes, while oral Wegovy is indicated for weight management.

The 2015 American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) clinical practice guidelines also note the importance of weight management in patients with type 2 diabetes and recommend the use of antihyperglycemic agents that are associated with weight loss or at least have a neutral effect on body weight (23)

Rodriguez-Valadez JM, Tahsin M, Fleischmann KE, et al

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Considering the large variety of therapies available, each with different attributes and mechanisms of action, along with the heterogenous nature of T2DM, the treatment landscape is understandably complicated