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Mild to moderate nausea typically peaks around day 3 to 4, then gradually lessens
Dean PG, Kukla A, Stegall MD, Kudva YC
But then, in 2021, the FDA approved a formulation of semaglutide for weight loss (brand name Wegovy)
Tirzepatide can cause stronger digestive side effects at higher doses
Most semaglutide patients do well with a quarter to half cup of low-glycemic fruit daily as part of balanced meals
