history of glp 1 agonists Frontiers The expanding landscape of GLP-1
Description
It uses the generic drug name (tirzepatide) rather than brand names (Mounjaro, Zepbound)
Within days to weeks, patients typically experience return of appetite, faster stomach emptying, and gradual weight regain as the medication's effects diminish
GIP may have a role in -/-cell crosstalk
Future generations of incretin agonists may be able to maintain the reduction in blood glucose and body weight while minimizing these off-target effects
Pricing starts at $399 per vial (varies with dose and titration)
doi: 10.1021/acs.jmedchem.5b00726, 88 le RouxC
