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Recent Developments: 2025: Eli Lilly received FDA approval for tirzepatide (Zepbound) as a treatment for moderate-to-severe obstructive sleep apnea in adults with obesity the first pharmacotherapy approved for this indication expanding tirzepatide's approved uses beyond metabolic conditions into a respiratory indication affecting over 30 million Americans and supported by SURMOUNT-OSA trial data showing 63% reduction in apnea-hypopnea index

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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Finan B, Ma T, Ottaway N, et al

Its not just extra pounds, but also where that fat is stored that changes in perimenopause (the years before your period stops) and menopause

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Further research is essential to clarify their role and optimize their integration into perioperative management protocols for orthopedic patients