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If you do not have a BMI over 35 but have a BMI over 30 and either have heart failure with preserved ejection fraction, chronic kidney disease stage three A or above, uncontrolled high blood pressure on two or more anti-hypertensive agents, then you qualify

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Article PubMed Google Scholar Mingrone, G

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This widespread receptor distribution has prompted investigation into potential pleiotropic effects, including anti-inflammatory properties that may contribute to their broader clinical benefits in cardiometabolic disease

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