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While gastrointestinal effects are well-documented, a growing number of patients and clinicians have begun discussing anxiety a side effect less talked about but increasingly relevant as these therapies expand

Studies show that consuming 30-40 grams of protein per meal triggers stronger GLP-1 release from intestinal cells compared to low-protein eating patterns, and this effect compounds when paired with soluble fiber from vegetables, beans, and whole grains

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R.Steinberg, Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression, Diabetes, Obesity and Metabolism (2026): 115, #MASLD #MASH #LiverHealth #MetabolicHealth #GLP1 #Obesity #Diabetes #Hepatology To view or add a comment, sign in Here the authors propose therapeutic advancement of the adipokine Adissp, an adipokine without a known receptor, that promotes an insulin-independent mechanism for glucose uptake and augments thermogenesis, representing a promising class of therapeutics for concurrently and synergistically treating insulin resistance, diabetes, obesity, and associated comorbidities