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Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) have increasingly been used to treat type 2 diabetes mellitus

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Reduced hepatic bilirubin clearance can be due to defective (i) unconjugated bilirubin uptake and intrahepatic storage, (ii) conjugation of glucuronic acid to bilirubin (e.g., Gilbert syndrome, CriglerNajjar syndrome, LuceyDriscoll syndrome, breast milk jaundice), (iii) bilirubin excretion into bile (DubinJohnson syndrome), or (iv) conjugated bilirubin re-uptake (Rotor syndrome)

Being careful not to touch the center of the patch, tear off the transparent film and remove the patch.2