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[DOI] [PubMed] [Google Scholar] Drucker DJ

ablation of the nausea-mediating AP, but not NTS, GLP-1R + neurons eliminates the conditioned taste avoidance response to semaglutide in rodents ( In summary, long-acting GLP-1R agonists primarily reach the circumventricular organs of the hindbrain and food-intake controlling centers of the hypothalamus

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When semaglutide or tirzepatide activates these receptors, neurotransmitter systems including dopamine, serotonin, and GABA shift in response
