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The brief examines the rapid growth in marketing of compounded versions of GLP-1 drugs following FDA-declared shortages that began in 2022

Multicenter study

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Ocular therapies with biomacromolecules: From local injection to eyedrop and emerging noninvasive delivery strategies

In doing so, we advocate for a paradigm that moves beyond traditional indications, embracing the full spectrum of GLP-1R agonists in areas such as primary prevention, microvascular protection, and metabolic liver disease, and metabolic disorders that include cardio-kidney-metabolic (CKM) syndromea systemic disorder characterized by interrelated metabolic, renal, and cardiovascular dysfunction and a broader cardio-renal-metabolic axis that includes central obesity, insulin resistance, dyslipidemia, hypertension, and pre-diabetic states

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