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Reporting from STAT News, found that compounded semaglutide has a shelf life of 30 to 60 days, which explains why many compounding pharmacies set conservative BUDs when they lack extensive in-house stability data

Butyrate ameliorates mitochondrial respiratory capacity of the motor-neuron-like cell line NSC34-G93A, a cellular model for ALS

Large trials like SUSTAIN demonstrated that semaglutide reduces cardiovascular events such as heart attack and stroke in patients with type 2 diabetes and heart disease, despite minor transient heart rate increases

Here, we show in both ex vivo and in vivo models of ischemic injury that treatment with GLP-1(2836), a neutral endopeptidasegenerated (NEP-generated) metabolite of GLP-1, was as cardioprotective as GLP-1 and was abolished by scrambling its amino acid sequence