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Description

GLP-1RAs have demonstrated potential in managing coexisting conditions associated with chronic inflammation, including obesity, dyslipidemia, and factors contributing to cardiovascular risk

Int J Obes 2020

Table 2 This table compiles current knowledge evaluating the impact of GLP-1 RAs on disease outcomes and safety in IBD patients

It's not uncommon, for example, to see some weight loss drugs negatively impact blood pressure and hypertension

Preclinical studies have indicated that GLP1RAs, such as tirzepatide, may directly impact the vasculature by enhancing endothelial function and decreasing inflammation, which are important in preventing atherosclerosis[30]