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Tirzepatide is a novel synthetic peptide that functions as a dual GIP and GLP-1 receptor agonist

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Triple-agonist compounds such as RETA are studied to explore whether simultaneous pathway engagement produces distinct signalling patterns compared to more limited receptor activation

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Researchers explain that semaglutide is considered a glucagon-like peptide (GLP-1) receptor agonist, which means it suppresses appetite

Interestingly, a cross-sectional study investigated the relationship between PhA and inflammation (measured by C-reactive protein, CRP) in 15 patients with PWS (28 6.8 years, 43.8 10.7 kg/m 2 ) compared to gender-, age-, and BMI- matched individuals without PWS (n = 15, 30 6.9 years, 43.9 8.8 kg/m 2 ) [80]