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, Beier, K
Together with dihydrobiopterin (BH2), BH4 forms a redox cycle that scavenges endogenous oxidative free radicals, thereby suppressing ferroptosis ( + /NAD(P)H as a cofactor ( De novo synthesis of BH4 depends on three enzymes: GCH1, 6-pyruvoyltetrahydropterin synthase (PTS), and sepiapterin reductase (SPR)
These discrepancies may stem from short observation periods and small sample sizes respectively (101, 102)
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It is often necessary for patients who have lost significant weight to achieve a snatched waistline
