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Owing to their potent glucose-lowering efficacy and substantial weight loss effects, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now considered part of the frontline therapeutic options to treat both type 2 diabetes mellitus and ...

With the highest 12 mg dose of retatrutide (Eli Lilly) an investigational #GLP1, glucose-dependent insulinotropic polypeptide (GIP) and glucagon receptor agonist nearly two-thirds of participants lost 20% or more of their body weight, half of participants lost 25% of their body weight and one-quarter of participants lost more than 30% of their body weight

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