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In combination with neuropsychiatric drugs, GLP-1RAs did not increase the risk of developing SSIBs

Orphan Drug Exclusivity provides seven years of marketing exclusivity for drugs approved for rare diseases (defined as affecting fewer than 200,000 Americans) [28]

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But also be cautious with sugar alcohols (maltitol in particular can spike blood sugar and cause GI distress), excess fiber supplements that can worsen constipation if not taken with adequate water, and heavily processed keto products that may contain hidden carbs or ingredients that exacerbate GLP-1 side effects

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2022, doi: 10.1016/j.cmet.2022.07.013