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Report Severe Reactions: If you notice significant redness, swelling, or pain, inform your healthcare provider

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If behavioral factors have shifted (reduced adherence to nutrition or activity), address those first while considering genetic testing to guide medication optimization

In mice, inhibiting NMDA receptor functions within the brainstem increases short-term dietary intake, but antagonizing them within the hypothalamus reduces food consumption and body weight

"Our data really shows that these behavioral changes persist over time, and the adoption curve resembles one of the fastest consumer disruptions on record," Furman told USA TODAY

However, this mechanism requires further investigation to establish its clinical relevance in humans