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These agents protect cells from inflammatory harm by reducing oxidative stress and supporting tissue equilibrium

Clinical trials demonstrate significant reductions in hepatic steatosis with semaglutide and liraglutide, though fibrosis improvement remains modest

3 These agents have also been shown to lower levels of circulating proinflammatory cytokines such as TNF- and IL-6, both implicated in HS pathogenesis, as well as C-reactive protein (CRP), a marker of systemic inflammation that correlates with disease severity

Evan Blum, MD

The incretin hormones glucagonlike peptide 1 and glucose-dependent insulinotropic polypeptide are neuroprotective in mouse models of Alzheimer's disease

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