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Due to the unique anatomical relationship between the CNS and the nasal cavity, relatively quick along with easy access for nanodrugs to the brain could be realized via intranasal administration

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Hair shedding typically peaks at months 4-8 of treatment, coinciding with the 2.4mg maintenance dose when weight loss is most rapid

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Over the past decades, metyrapone has been extensively used as off-label therapy in the management of CD patients