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Space away from other medications by at least 1 hour

In contrast to other AOMs, which either suppress appetite or inhibit fat absorption [23], GLP-1RAs reduce body weight in a number of ways, decreasing appetite and hunger, and increasing satiety, resulting in reduced energy intake [2426]

Most people improve within a few days

According to Sinha et al., tirzepatide has better efficacy compared to many glucose-lowering medications such as dulaglutide, glargine, semaglutide, and insulin degludec and placebo drugs [14]

* Liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound) are also FDA-approved for weight loss and weight management in patients with obesity without diabetes