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Other molecules targeting fatty acid synthesis or de novo lipogenesis, such as DGAT2i (NCT04399538) or TVB-2640 (NCT03938246, NCT04906421) have been tested in phase 2 trial alone or in combination with other compounds

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These medications represent a promising frontier in the ongoing effort to combat obesity and its associated health risks

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doi: 10.1016/j.apsb.2021.12.011

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