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Glucose, metformin, and AICAR regulate the expression of G protein-coupled receptor members in INS-1 beta cell

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Source: West, S et al Weight regain after cessation of medication for weight management: systematic review and meta-analysis, BMJ January, 2026 Newer incretin mimetics are the GLP-1 medications semaglutide and tirzepatide

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If tirzepatide insomnia or semaglutide insomnia is an issue, avoid stimulating add-ins like cocoa powder or matcha, and keep the smoothie smaller than your morning portion to avoid lying down with a full stomach