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However, the role of GLP-1R in the pathological process of OA is unclear

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Diabetes leads to a significantly accelerated incidence of various related macrovascular complications, including peripheral vascular disease and cardiovascular disease (the most common cause of mortality in diabetes), as well as microvascular complications such as kidney disease and retinopathy

Though each of these medications has its differences, they all belong to a class of drugs known as GLP-1 receptor agonists, which means they imitate a hormone in the body called glucagon-like peptide-1