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In patients with volume depletion, correct this condition before initiating XIGDUO XR [see Warnings and Precautions (5.3) and Use in Specific Populations (8.5, 8.6)]

Steady-state pharmacokinetics represent another injectable advantage

This is relevant to the Strive Pharmacy conversation because the compounded tirzepatide they produce should, in theory, activate both of these pathways identically to brand-name Mounjaro

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Science 271 , 994996 (2016)