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If nausea turns into vomiting, the risk of severe dehydration increases rapidly

The 12 mg dose subgroup showed the greatest reduction with an MD of 1.54 (95% CI: 2.47 to 1.55, P = 0.14), with significant heterogeneity ( P = 0.00001, I 2 = 98%) ( Table 3 , Supplemental Figure S7)

however, the exact amount of MO per tablet was not specified and basal differences were observed between MO and control groups in initial HbA1c, which decreases somehow the resulting evidence grade since the subjects under MO treatment started with a worse glucose control than the other group

Daily GIP injections led to a decrease in the adipose tissue gene expression levels of pro-inflammatory cytokines, such as Il-1 beta, Il-6, TNF-alpha in wild-type mice, 60 while blood levels of adiponectin, an anti-inflammatory and insulin-sensitizing adipokine, are enhanced

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