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Meanwhile, orforglipron demonstrated significant weight loss efficacy [8] consistent with injectable GLP-1 medicines

Tirzepatide, a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, has emerged as a groundbreaking treatment for Type 2 diabetes mellitus (T2DM) and obesity

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Conclusions GLP-1RAs had a neutral effect on the composite cardiovascular outcomes but reduced composite kidney events in the patients with advanced DKD compared with DPP-4is.

Shares in Amgen fell on Tuesday after they announced the results of a trial for their weight loss drug MariTide.