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By combining data from observational and Mendelian randomization (MR) studies, we aimed to investigate whether GLP-1 RAs decrease the risk of DR

To overcome this limitation, various modifications and delivery strategies to enhance the pharmacokinetic properties and therapeutic efficacy of GLP-1 analogs have been studied

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Five scientists won this years Breakthrough Prize in Life Sciences for their work on GLP-1 and the development of drugs for diabetes and obesity.