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The real question is not how much weight is lost, but how much visceral fat, liver fat, cardiovascular risk, and CKD progression can be reduced

During the early stages of development, tesofensine was found to be ineffective in treating neurodegenerative conditions, but it unexpectedly caused weight loss in the people who took it

It could also eat into the somewhat messy business of organizations that today use secondary use to provide data sourced over health information networks to clinical trials and life science companies, like Pluto Health

Most of our weight loss treatments are well-tolerated, but some patients may experience mild side effects such as nausea, headaches, or injection site discomfort

The SmPC also notes that rodent studies showed C-cell thyroid tumours, though the human relevance is unknown

The mechanism likely involves modulation of pain signaling pathways and endorphin release