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Despite this record enrollment, there remains federal uncertainty around enhanced premium tax credits
A recent meta-analysis performed on patients with T2DM showed that all GLP-1 dose groups had a significantly higher incidence of vomiting compared to both placebo and conventional therapy, especially in individuals treated with exenatide [51]
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While semaglutide was initially approved primarily for diabetes management, it has increasingly been prescribed off-label by weight-loss specialists due to its remarkable results in clinical trials
The global GLP-1 market exceeded $70 billion in 2025 and is projected to reach over $200 billion by 2033 ( [17] )
