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Interestingly, although the great majority of samples originating from insulinoma cases had GLP1R-expressing acini, the percentage of cases with positively immunostained acini was lower in samples originating from chronic pancreatitis or ductal pancreatic carcinoma (Table 2)

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This drop-off may be attributed to a subset of patientsoften impulse buyersseeking rapid weight loss rather than committing to long-term therapeutic regimens

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doi: 10.1016/S0140-6736(19)31150-X 15 GersteinH

Mechanism of Action 17.3.8