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Affected individuals develop uncontrolled choreiform movements, cognitive decline, and psychiatric symptoms including depression and anxiety

Common side effects include: Nausea Vomiting Diarrhea Constipation Headache Fatigue Indigestion These happen because the medication slows digestion and affects appetite signals in the brain and small intestine

This is especially important for individuals over 40, who naturally lose muscle mass with age

PD-1 inhibitors halt this pathway to avoid T cell exhaustion

Fortunately, due to the shortages of these medications, compounding pharmacies have been allowed to make the same medication available at a much cheaper price for those who can inject themselves once a week with a tiny needle
