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Mentre in passato la sua influenza sulle cardiopatie era discussa, in seguito diverse societ scientifiche, in particolare lEASO, hanno provato e definito che lobesit va considerata una malattia cronica e recidivante cui si legano molte complicanze

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demonstrated that GLP1R expression was significantly reduced in the endothelial and smooth muscle cells of db/db mice, with the transcription factor TCF7L2 implicated as a possible upstream regulator [79]

For decades, scientists believed adults had negligible brown fat