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When semaglutide activates these pathways, some patients experience heightened sensitivity to dehydration, signaling your brain that fluid intake is needed even if your body's actual hydration status is adequate

Hoevenaars, Lars Verschuren, Robert Kleemann, Jildau Bouwman, Gabriele V

(2) reflections on the diverse impact on mental health

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GLP-1 helps with blood sugar control and weight loss by: Stimulating your pancreas to release insulin, which helps control your blood sugar Slowing the rate at which food passes from your stomach to your intestine, which helps you feel full for longer Stopping your liver from releasing extra glucose into your blood, which helps to manage your blood sugars and reduces insulin resistance Sending signals to your brain that you are full and helping reduce cravings (food noise) by 'calming' your brain's reward centres Glucose-dependent insulinotropic polypeptide (GIP) This is another gut hormone that helps you lose weight and regulates your blood sugar

It's not in your head