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It is important to emphasise that GLP-1 receptor agonists are not currently licensed specifically for treating inflammatory conditions in the UK

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Abbreviations AEs adverse events BC body composition BHB -hydroxybutyrate BIA bioelectrical impedance analysis BIVA bioelectrical impedance vector analysis BMI body mass index BW body weight CT computed tomography CVD cardiovascular disease FM fat mass FFM free fat mass GI gastrointestinal GLP-1 glucagon-like peptide-1 GLP-1RA glucagon-like peptide-1 receptor agonist HFpEF heart failure with preserved ejection fraction KD ketogenic diet LBM lean body mass MASH metabolic dysfunction-associated steatohepatitis MD Mediterranean diet MEAL Muscle maintenance, Energy balance, Avoid side effects, Liquid intake MM muscle mass MNT medical nutrition therapy MRI magnetic resonance imaging PUFA polyunsaturated fatty acids RCTs randomised controlled trials SCFAs short-chain fatty acids STEP Semaglutide Treatment Effect in People with obesity T2D type 2 diabetes TNF tumor necrosis factor VLCKDs very-low-calorie ketogenic diets VLEKT very low energy ketogenic therapy WC waist circumference WHO World Health Organization Author Contributions Conceptualization: LV, GM

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