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These typically improve over 48 weeks

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February 25, 2026: Zepbound Label Updated with Warning of Severe Gastrointestinal Issues The FDA has posted an updated Zepbound warning label, which includes reports of gastrointestinal issues that patients claim they experienced after Zepbound reached the market

Semaglutide is one of the most effective weight loss drugs available and your results can be remarkable

However, metformin has decades of safety data, costs considerably less, and both medications can cause gastrointestinal side effects