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doi: 10.1038/s41569-023-00849-3

16-18 Nausea is the most frequently reported AE among GLP-1 RAs, with rates ranging from 20% to 40% depending on the agent and dose

In the controlled adult trial (Study 7), 6% (21/358) of VYVANSE-treated patients discontinued due to adverse reactions compared to 2% (1/62) of placebo-treated patients

High waist circumference specifically has been linked to numerous health risks: Hypertension (high systolic blood pressure) Diabetes mellitus (high blood glucose levels) Hypercholesterolemia (high triglycerides) Joint and low back pains Hyperuricemia (high uric acid levels) Obstructive Sleep Apnea Syndrome In Summary A year ago I believed GLP-1 medications were simply another tool of diet culture

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Metabolic-Immune Crosstalk Metabolic dysfunction, particularly insulin resistance and MASLD, amplifies systemic inflammation and contributes to autoimmune disease activity [50,51]