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Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-/JAK1/STAT1/IRF-1, TLR-4/NF-B/IL-6, and JAK2/STAT3/COX-2 crosstalk

All results were statistically significant except the heart failure finding

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If your BMI is 40+ and you need substantial weight reduction for health reasons, the 20-25% body weight loss achievable with tirzepatide vastly exceeds the 10% typical of Qsymia

Its thought that these additional benefits are tied to weight loss