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Lilly announced the topline results from its phase 3b "TOGETHER PsA" trial, showing that the combination use of ixekizumab (Taltz) and tirzepatide (Zepbound) was superior to IXE alone, yielding both significant weight loss and ACR50 disease control in adults with active psoriatic arthritis (PsA).

Adipokines (e.g., leptin and adiponectin) are regulated by DPP-4 and may influence bone remodeling and energy metabolism in a paracrine manner

PlexusDx explains the interaction risks, safe alternatives, and how to manage pain during GLP-1 therapy

Build sustainable habits for nutrition, mindset, and long-term success beyond medication.

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But it may become another tool, carefully selected, closely monitored, and integrated with diabetes technology