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Their structure is based on the peptide sequence of a compound found in the saliva of the Gila monster lizard and they are resistant to degradation by the enzyme DPP-4

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( 10.2174/1573399811309020007) [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Nauck MA, Kemmeries G, Holst JJ, Meier JJ
Conversion charts exist to help guide dosing during these within-class switches
Press Release June 18 2020
December 11, 2023