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For example, Bak et al

These data provide an explanation for CNS activation even though monoclonal antibodies have minimal brain penetrance, reaching concentrations of around 0.10.4% of the monoclonal antibody concentrations in the plasma 50,51

These included reproductive symptoms, including irregular menstrual cycles and unexpected bleeding, and temperature-related issues, such as chills, hot flashes, and feeling unusually cold

American Psychological Association
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The pancreas produces insulin only when needed
