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Clinical trials are underway to see whether the drugs can reduce the risk of heart attack, stroke, kidney disease and other chronic diseases in people with obesity

Side effects may temporarily increase around a dose change, then settle as the body adapts
If controlling weight is one of your goals, your total calorie intake is also important
Semaglutide British National Formulary

Schedule consistent follow-ups to review progress, adjust doses if necessary, manage side effects, and provide ongoing lifestyle guidance
The vast majority of the disease's genetic architecture is non-Mendelian, driven by polygenic risk factors interacting with environmental triggers that remains largely uncharacterized [46, 48, 54]
