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Even the lowest tirzepatide dose (5 mg) outperformed semaglutide 1.0 mg for weight loss

Currently, GLP-1 medications are not FDA-approved for RA treatment
Warning Letters: In September 2025, the FDA issued over 50 Warning Letters to companies illegally marketing Retatrutide

Common side effects may include nausea, vomiting, diarrhea, constipation, fatigue, and acid reflux

Mozaffarian D et al

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