are glp 1 safe for teens GLP-1s teens?" is common question parents ask. One of our pediatric endocrinologists shares a list of further questions parents can ask their doctor when considering the medication for Researchers at UC Irvine issue

Indeed, studies on the use of GLP-1Ra mostly included patients with diabetes who were administered a dose used in this condition, did not have adequate bone parameters as primary endpoints, and had short follow-up periods

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In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1