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GLP-1 agonists offer metabolic and anti-inflammatory benefits, but appetite suppression may drive gut microbiome dysbiosis that offsets long-term outcomes.

3 min readThe First Quarter 2026 newsletter of AHA Coding Clinic for ICD-10-CM and ICD-10-PCS is now available

Circana studied changes in purchases and consumption among GLP-1 users and identified marked differences in behavior during the first three months of GLP-1 usage versus months 10-12

The beneficial effect of TZT in T2DM and obesity is related to direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight

However, there is much more to this lipid molecule than meets the eye